Metabolic alterations affiliated with T2D are very well characterised by epidemiological and research based research. The pathogenesis and development of T2D is ascribed to 4 mechanisms; elevated Highly developed glycation conclude solution (AGE) development, elevated polyol pathway flux, activation of protein kinase C (PKC) isoforms, and enhanced hexosamine pathway flux[7]. https://www.directivepublications.org/journal-of-diabetology-research/