This mechanism might be from the induction of hepatic microsomal enzymes that metabolize the antibiotic. If phenobarbital and doxycycline are administered concurrently, the medical reaction to doxycycline need to be monitored carefully. Phenytoin, sodium valproate, valproic acid: The effect of barbiturates over the metabolism of phenytoin seems to generally be https://anatolen901wsm7.wikicorrespondent.com/user