even more illuminating issues, purpose and therapeutic efficacy of MSCs are hugely regulated by the surrounding area of interest/microenvironment (Zhu et al., 2016; Mehrbani Azar et al., 2018; Tejero et al., 2019; https://bookmarksaifi.com/story18399355/the-single-best-strategy-to-use-for-mesenchymal-stem-cells-definition