There exists a release of norepinephrine through the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors within the dorsal horn to lower afferent suffering transmission and produce analgesia. Therefore, medicine like clonidine that target alpha-two receptors can impact the transmission of ache. Relates to clonidine: oral tablet, oral pill https://michaely602bvs0.jasperwiki.com/user