In this article, we clearly show that conolidine, a natural analgesic alkaloid used in classic Chinese medicine, targets ACKR3, thereby supplying supplemental proof of the correlation among ACKR3 and pain modulation and opening alternate therapeutic avenues to the treatment of Continual agony. Endorse a way of relaxation and wellbeing: https://peterr369trm9.blog-kids.com/profile