Pentobarbital will decrease the level or effect of ketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of meloxicam by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of solifenacin by affecting hepatic/intestinal enz... https://travialist.com/story10600690/non-ci-sono-altre-pentobarbital-hond-un-mistero